My top tip today for Vista, is actually an IE7 tip.
We all know that if you have the Glass interface turned on then Windows-Tab will give you a nice funky app switcher.
With a few tabs open try pressing CTRL-Q
You will get a window showing a thumbnail of all the open tabs, you can now either just click the tab you require, or use the cursor keys to navigate around and use Enter to select. You can also click the x at the top right to close tabs you no longer require.